Prevalence of variant hemoglobins and thalassemias in a maroon community in Sergipe, Brazil

Elizano Santos de Assis, Jamille Alves Araújo, Maria Izabel Ribeiro Cabral de Rezende, Cristiane Costa da Cunha Oliveira, Francisco Prado Reis, Cláudia Moura de Melo

Resumo


Current analysis investigates the sickle-cell syndrome among members of a maroon community (comunidade quilombola) in the state of Sergipe, Brazil. The entire population, comprising five hundred and ninety-three people, was screened. Blood samples were collected from 318 people, aged between six months and fifty years, who underwent a solubility test to assess the presence of HbS, followed by Sickle-Cell Test to confirm its presence. Results revealed that 2.2% of the three hundred and eighteen people tested have hemoglobin HbS in their blood; 57% have type HbAS and 43% have a combination between thalassemia and heterozygous with a variable percentage of HbS ranging between 24.9 and 37.9%. Blood sampling revealed that only five out of the 318 people belonged to different families. Results are highly relevant for public health policies on the sickle-cell syndrome and its management.

 


Palavras-chave


sickle cell syndrome; maroon community; diagnosis.

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DOI: http://dx.doi.org/10.4025/actascihealthsci.v37i2.23444

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ISSN 1679-9291 (impresso) e ISSN 1807-8648 (on-line) e-mail: actahealth@uem.br

  

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